Gene Flaws Common in Blacks With Breast Cancer
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Genetic mutations that raise the risk of breast cancer, like the kind Angelina Jolie has, are surprisingly common in black women with the disease, according to a new study that could help explain why blacks face higher rates of breast cancer. (June 3)


(SUPER = Chicago)(NATS - Alicia Cook)"This is my mom. She passed away at the age of 49 with ovarian cancer."GENERATIONS OF CANCER RUN IN ALICIA COOK'S FAMILY.(NATS - Alicia Cook)"This is my middle sister Pam. She passed away at the age of 44 with breast cancer."(SOT)(SUPER = Alicia Cook, Breast cancer survivor)"Then I was diagnosed with breast cancer in 2003."SCIENTISTS ALREADY KNOW MUTATIONS IN CERTAIN GENES, THE BRCA -1 (BRAK'-uh) OR BRCA - 2 GENE, CAN BE INHERITED... AND PUT WOMEN AT A MUCH HIGHER RISK OF GETTING BREAST AND OVARIAN CANCER AT A YOUNG AGE.(NATS - Alicia Cook)"I have a large deletion in my BRCA-1 gene."ANGELINA JOLIE REVEALED SHE TOO HAS A BRCA-1 MUTATION AND HAD A PREVENTIVE DOUBLE MASTECTOMY.BUT A NEW STUDY FOUND HOW COMMON THE MUTATIONS ARE IN BLACK WOMEN WHO DID DEVELOP BREAST CANCER - ONE/FIFTH HAD BRCA MUTATIONS.THE FINDINGS COULD HELP EXPLAIN WHY BLACKS FACE HIGHER RATES OF MORE AGGRESSIVE BREAST CANCERS.(SOT)(SUPER = Dr. Jane Churpek, Oncologist, University of Chicago)"African-American women are more likely to get breast cancer at a young age, meaning less than age 45 than white women. We also know that once a black woman is diagnosed with breast cancer, she's more likely to die of that breast cancer than a white woman."DOCTOR JANE CHURPEK (CHUR'-pehk) LED THE STUDY.(SUPER = File)SHE SAYS MORE BLACK WOMEN WITH A FAMILY HISTORY OF BREAST OR OVARIAN CANCER SHOULD SEEK GENETIC COUNSELING TO UNDERSTAND THEIR RISK AND PREVENTION OPTIONS. (SOT)(SUPER = Dr. Jane Churpek, Oncologist, University of Chicago)"We can also focus on preventing cancer for the next generation."(SOT)(SUPER = Alicia Cook, Breast cancer survivor)"My twelve-year-old daughter asked me about our family history and breast cancer."COOK SAYS IF SHE KNEW ABOUT HER GENETIC RISK EARLIER SHE MAY HAVE HAD HER BREASTS REMOVED LIKE JOLIE.COOK'S GRATEFUL HER DAUGTHER MAY HAVE MORE INFORMATION THAN SHE DID.